ncRNA name | MALAT1 |
ncRNA Category | lncRNA |
ID | 378938 |
Ensembl | ENSG00000251562 |
Synonyms | HCN, LINC00047, MALAT-1, NCRNA00047, NEAT2, PRO1073, mascRNA |
Disease name | diabetic retinopathy (DR) |
Species | Homo sapiens |
Tissues/Cell_line | aqueous humor, fibrovascular membranes |
Methods | microarray, qPCR |
Expression pattern | up-regulated |
Functional description | Approximately 303 lncRNAs were aberrantly expressed in the retinas of early DR, including 214 downregulated lncRNAs and 89 upregulated lncRNAs. In addition, MALAT1 was significantly upregulated in an RF/6A cell model of hyperglycemia, in the aqueous humor samples, and in fibrovascular membranes of diabetic patients. |
PubMed ID | 24436191 |
Year | 2014 |
Title | Aberrant expression of long noncoding RNAs in early diabetic retinopathy. |
Drug-related ncRNA | NO |
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